hrp0092p1-397 | Pituitary, Neuroendocrinology and Puberty (2) | ESPE2019

Questioning the Value of Brain MRIs in the Evaluation of Children with Isolated Growth Hormone Deficiency

Oren Asaf , Singer Dana , Rachmiel Mariana , Hamiel Uri , Shiran Shelly , Ben-Sira Liat , Schachter-Davidov Anita , Eyal Ori

Background: Isolated growth hormone deficiency (IGHD) is a relatively common disorder. Current diagnostic protocols require a brain MRI of the hypothalamus and the hypophysis after establishment of the diagnosis, with the aim of identifying structural defects and specifically rule out an underlying space-occupying lesion. An MRI scan is costly and requires general anesthesia in young children. Data on the contribution of brain MRI in diagnosing children with I...